I agree with Jedi. I play directly into a tube amp (fender deville 410) with an stock guitar (ibanez s470gxqm my dad gave me), i turn the bass all the way down and the high and mid all the way up, and perhaps a slight reverb. I get a sound kind of like Vic from playin dead on the middle pickup, and a bertha/saint steven sound on my bridge pickup. The amp also has a foot switch i mess around with makes it sound a bit dirtier... I dont really know much about all the tone stuff, but im sticking with my guitar straight into my amp, and let my fingers be responsible for the jerryness. I am however gonna try to get some super 2's or something.
ill post a sound byte if u'd like. Hope this helps.
Adam