How close to "awesome" do you want to be? Wrestling a Twin with E-120s is not too bad if you put casters on it, just a bitch lifting it in and out of the car and, god forbid, if there are stairs at the venue. Years ago I was alarmed to see the overweight guitarist I was playing with redfaced and puffing as he struggled to get his Twin up a steep flight of about 24 stairs. Not alarmed enough to actually CARRY it for him -- I had my own stuff to haul at that point. He survived.
Splitting the Twin into a head and carrying the E-120s into 1X12 cabinets ... I went down the road, too. It's slightly more convenient, although it does not reduce the overall weight of the setup, just makes it two separate carries. The same is really true with the rack system and separate cabinets ... did that, as well, but wound up with a 6-space rack for the pedals and GCX and a 4-space for the preamp and reverb. Put the 2X12 in a real road case with rollers and carried a dog ramp to muscle it up into the wagon. Stairs became the bane of my existence, as well as stages a few feet high with no ramps.
No questions the JBLs and Twin setup is the most authentic way to get the sound, assuming you have the right guitar and a good touch. Unfortunately, that does not come with Steve Parish to haul it, so you can either put up with it or compromise.
For me, as I got more into my 40s I decided that "close enough" was "good enough" and the last couple years have been using a Fractal AX8 floorboard and going direct to FOH. If the venue has good monitors (QSC K12s are everywhere now), all I need to carry is the floorboard and the guitar. Setup and teardown in 3 minutes. If I need a monitor I have an Atomic CLR Neo that is plenty loud enough and sounds great to me. Have also used QSC K12s and K10s -- the K10 is fairly light and compact.
I love having a rig I can actually walk on a plane with. But this is also a place with knowledgeable people who have dissected Jerry's tone down to the finest points, but to achieve that, you have to get the proper components. It's anyone's guess as to what ol' Jer would be using these days.