Other than the name they are nothing like the MC50 or mc250 etc... in tone. I am sure it would work, but I have no idea what it will sound like. Those latter models guitar players use are great because of the old school circuitry and the transformers/autoformers they have. The new ones are nothing like it from what I see. I actually looked in to those too. I would guess it would be like a stab in the dark if it will sound good or not, and I would guess not since they are optimized for car stereos, but who knows? It may be easier to try a cheaper one and see how it performs. It may clip and shut down or something annoying like that.